What is the prognosis of eosinophilic esophagitis (EoE)?

Updated: Jan 03, 2020
  • Author: Nina Tatevian, MD, PhD, FCAP; Chief Editor: Nirag C Jhala, MD, MBBS  more...
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Answer

Answer

Eosinophilic esophagitis (EoE) is a chronic, antigen-driven inflammatory disease with an allergenic nature of antigen. Current therapies include dietary therapy, topical steroids, and proton pump inhibitors, [59, 60, 61]  as well as endoscopic dilation in cases with strictures. [61, 62] The disease has been seen to remit with treatment such as dietary exclusions of antigenic foods and/or topical steroids. [3, 63, 64]

More recently, investigational therapies include "novel, esophageal-targeted formulas of topic corticosteroids, and monoclonal antibodies (including mepolizumab, reslizumab, QAX576, RPC4046, dupilumab, omalizumab, infliximab and vedolizumab)." [61]

Since EoE is a recently recognized entity, the natural history of EoE and predictive factors of complications are yet unknown. [2]


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