What are the contraindications to nitroglycerin in coronary computed tomography angiography (CCTA)?

Updated: Dec 21, 2017
  • Author: Eugene C Lin, MD; Chief Editor: Eugene C Lin, MD  more...
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Answer

Answer

The administration of sublingual nitroglycerin dilates the coronary arteries and increases side branch visualization. [5] Nitroglycerin is contraindicated in patients who are allergic to it and in patients who are taking phosphodiesterase inhibitors for erectile dysfunction. [6] Patients should not have taken a phosphodiesterase inhibitor for at least 48 hours before the exam. The concomitant use of phosphodiesterase inhibitors can cause severe hypotension. Nitroglycerin can cause orthostatic hypotension and should be used with caution in patients who have low systolic blood pressure (eg, http://emedicine.medscape.com/article/1612388-overviewhypertrophic cardiomyopathy</a> can also be aggravated.


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