How do outcomes with coronary computed tomography angiography (CCTA) compare with functional testing in coronary artery disease (CAD)?

Updated: Dec 21, 2017
  • Author: Eugene C Lin, MD; Chief Editor: Eugene C Lin, MD  more...
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Answer

In the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) trial, [27] a strategy of initial CCTA showed no mprovement in clinical outcomes over a median follow-up of 2 years compared with functional testing. The investigators randomized 10,003 symptomatic patients to initial testing with eiher CCTA or functional testing (exercise electrocardiography, nuclear stress testing, or stress echocardiography). Although more patients in the CCTA group than the functional testing group underwent catheterization within 90 days, those in CCTA group also had with fewer catheterizations showing no obstructive CAD. [27]


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