What is the role of the CBC count in the workup of unstable angina?

Updated: Oct 01, 2020
  • Author: Walter Tan, MD, MS; Chief Editor: Eric H Yang, MD  more...
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Answer

The complete blood cell (CBC) count helps in ruling out anemia as a secondary cause of acute coronary syndrome (ACS). Leukocytosis has prognostic value in the setting of acute myocardial infarction (MI). Early changes in platelet size and number appear to occur in those with ACS. [27] In a prospective study of 134 patients with ACS (unstable angina, non-ST elevation MI [NSTEMI], STEMI), investigators found that platelets and mean platelet volume decreased within 3 hours of admission, whereas at 72 hours and 7 days, these values increased only in those with acute MI. [27]


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