Which drugs are used to treat Wolff-Parkinson-White (WPW) syndrome?

Updated: Jan 08, 2017
  • Author: Christopher R Ellis, MD, FACC, FHRS; Chief Editor: Mikhael F El-Chami, MD  more...
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Answer

Class Ic drugs (eg, flecainide, propafenone) are typically used with an AV nodal blocking agent in low doses to avoid atrial flutter with a 1:1 conduction. class III drugs (eg, amiodarone, sotalol) are also reasonable choices, although these agents are less effective for altering accessory pathway conduction properties. Class Ic drugs should not be given if the patient has structural heart disease (coronary artery disease, myocardial infarction, congestive heart failure, left ventricular hypertrophy). Class Ic drugs are typically used with an AV nodal blocking agent.


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