What is the role of procainamide and esmolol in the treatment of Wolff-Parkinson-White (WPW) syndrome?

Updated: Jan 08, 2017
  • Author: Christopher R Ellis, MD, FACC, FHRS; Chief Editor: Mikhael F El-Chami, MD  more...
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Procainamide and esmolol are available for use in resistant cases but should only be administered by physicians familiar with these medications. Verapamil should not be administered to patients younger than 1 year because of risk of severe hypotension, severe bradycardia, or heart failure in this population of patients; this drug has also been reported to accelerate the ventricular rate in AF, leading to rapid conduction that results in ventricular fibrillation (VF).

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