When is IV adenosine indicated in the treatment of cardiac arrest with hemodynamic compromise Wolff-Parkinson-White (WPW) syndrome?

Updated: Jan 08, 2017
  • Author: Christopher R Ellis, MD, FACC, FHRS; Chief Editor: Mikhael F El-Chami, MD  more...
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Answer

When conservative measures fail, intravenous (IV) access is necessary. Adenosine is the first-line agent and is effective in approximately 90% of reentrant narrow-complex tachycardias. Adenosine must be administered as a rapid bolus because of its short half-life. Most instances of adenosine failure in this setting are caused by inadequate administration of the drug. A defibrillator must be available in the event that new dysrhythmias emerge, particularly postadenosine AF.


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