What is the role of blood serum measurement of medications in the management of Wolff-Parkinson-White (WPW) syndrome?

Updated: Jan 08, 2017
  • Author: Christopher R Ellis, MD, FACC, FHRS; Chief Editor: Mikhael F El-Chami, MD  more...
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Answer

Blood levels of antiarrhythmic medications during therapy and monitoring are typically not helpful for oral medications. Intravenous (IV) lidocaine and procainamide do require serum measurements during treatment. Digoxin is a medication that should typically be avoided in WPW patients because of a preferential decrease in atrioventricular (AV) nodal, rather than pathway, conduction. However, digoxin levels may be helpful if digoxin toxicity is suspected.


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