How does intermittent preexcitation affect the disease course of Wolff-Parkinson-White (WPW) syndrome in children?

Updated: Jan 08, 2017
  • Author: Christopher R Ellis, MD, FACC, FHRS; Chief Editor: Mikhael F El-Chami, MD  more...
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However, a more recent study suggested that children with intermittent preexcitation do not have a lower-risk APs as measured by EPS criteria or reduced symptoms. [24] The investigators evaluated data from 295 children (1996-2013), comparing those with persistent, intermittent, or loss of preexcitation Holter/Holter testing. Although there were no baseline differences in high-risk pathways among these groups, the inclusion of isoproterenol values demonstrated an increased frequency of high-risk pathways among children with loss of preexcitation on Holter/Holter testing (54% vs 16% persistent, 11% intermittent).

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