What are the death rates for Wolff-Parkinson-White (WPW) syndrome?

Updated: Jan 08, 2017
  • Author: Christopher R Ellis, MD, FACC, FHRS; Chief Editor: Mikhael F El-Chami, MD  more...
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In a study that evaluated the long-term (median, 6.9 y) natural history of WPW in adult patients treated with (n = 872) and without catheter ablation (n = 1461) compared to a control group (n = 11,175), Bunch et al found similarly low death rates but higher incident AF risk in patients with WPW versus the control group. [20]  The risk of long-term mortality was higher in those who did not undergo ablation compared to the group treated with ablation, whereas the risk of incident AF was higher in the ablation group. Thus, ablation did not reduce the risk of AF.

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