What is the incidence of Wolff-Parkinson-White (WPW) syndrome in the US?

Updated: Jan 08, 2017
  • Author: Christopher R Ellis, MD, FACC, FHRS; Chief Editor: Mikhael F El-Chami, MD  more...
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The incidence of preexcitation and WPW syndrome ranges from 0.1 to 3 cases per 1000 population (average, 1.5 cases per 1000 population) in otherwise healthy persons. This includes only patients with manifest preexcitation (delta wave evident on surface 12-lead ECG). About 60-70% of these individuals have no other evidence of heart disease. Approximately four newly diagnosed cases of WPW syndrome per 100,000 population occur each year.

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