What is the role of orthodromic tachycardia in the pathogenesis of Wolff-Parkinson-White (WPW) syndrome?

Updated: Jan 08, 2017
  • Author: Christopher R Ellis, MD, FACC, FHRS; Chief Editor: Mikhael F El-Chami, MD  more...
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Answer

When a premature ectopic atrial impulse advances towards the ventricle, it has the potential to block at the AP but conduct down the normal AVN/His Purkinje pathway. The impulse then reenters the AP in a retrograde fashion to perpetuate a circus movement of the impulse. Such reentrant tachycardia is described as orthodromic. Premature ventricular contractions (PVCs) can also initiate orthodromic tachycardia.


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