How is preexcitation in Wolff-Parkinson-White (WPW) syndrome defined?

Updated: Jan 08, 2017
  • Author: Christopher R Ellis, MD, FACC, FHRS; Chief Editor: Mikhael F El-Chami, MD  more...
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Answer

Although "preexcitation" was first coined by Ohnell in a landmark publication in 1944, the term as defined by Durrer et al in 1970 provided a better description in the literature of what an accessory pathway is (before the advent of invasive electrophysiologic studies and ablation provided a clearer understanding): "Preexcitation exists, if in relation to atrial events, the whole or some part of the ventricular muscle is activated earlier by the impulse originating from the atrium than would be expected if the impulse reached the ventricles by way of the normal specific conduction system only." [6]


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