Which medications in the drug class Electrolytes are used in the treatment of Ventricular Tachycardia?

Updated: Dec 05, 2017
  • Author: Steven J Compton, MD, FACC, FACP, FHRS; Chief Editor: Jeffrey N Rottman, MD  more...
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Electrolytes are considered therapeutic alternatives for refractory VT. Patients with persistent or recurrent VT after administration of antiarrhythmic drugs should be assessed for underlying electrolyte abnormalities as a cause of their refractory dysrhythmia. Electrolyte abnormalities that may be associated with VF include hyperkalemia, hypokalemia, and hypomagnesemia.

Magnesium sulfate, calcium chloride, and sodium bicarbonate are used in VT secondary to other medications. Magnesium sulfate acts as an antiarrhythmic agent. Sodium bicarbonate is used as an alkalinizing agent, and calcium chloride is used to treat VT caused by hyperkalemia.

Magnesium sulfate (MgSO4)

Magnesium sulfate is the agent of choice for torsades de pointes. It also may be useful for treating conventional VT, especially in patients with confirmed hypomagnesemia. Patients treated with magnesium sulfate require monitoring for hypermagnesemia; an overdose can cause cardiorespiratory collapse and paralysis.

Calcium chloride

Calcium chloride is useful for the treatment of hyperkalemia, hypocalcemia, or calcium-channel blocker toxicity. It moderates nerve and muscle performance by regulating the action potential excitation threshold.

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