What is the role of lab tests in the workup of ventricular premature complexes (VPCs)?

Updated: Nov 26, 2016
  • Author: Jatin Dave, MD, MPH; Chief Editor: Jose M Dizon, MD  more...
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Answer

Obtain laboratory studies to evaluate or correctable causes of VPCs, such as medications, electrolyte disturbances, infection, and myocardial ischemia or MI. Obtain serum electrolyte and magnesium levels.

A 2016 population-based study of 498 individuals with ventricular ectopy activity, including PVCs, found that elevated levels of N-terminal pro-B-type natriuretic peptide (NT-proBNP) were independently associated with ventricular ectopy but not with levels of high sensitivity-troponin I (hs-TnI) or hs-C-reactive protein (hs-CRP). [13] Obtaining levels of NT-proBNP may help in the evaluation of potential adverse cardiovascular events in persons with asymptomatic ventricular arrhythmias.


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