What is the role of medications in the treatment of sinus node dysfunction (SND)?

Updated: Nov 30, 2018
  • Author: Bharat K Kantharia, MD, FRCP, FAHA, FACC, FESC, FHRS; Chief Editor: Mikhael F El-Chami, MD  more...
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Currently, no medications are routinely used to treat symptomatic sinus node dysfunction (SND). Virtually most medications are ineffective over the long term, and many demonstrate lack of efficacy from tachyphylaxis. Nonetheless, acute treatment with the anticholinergic agent atropine and/or the adrenergic agonist isoproterenol may be warranted. Oral analogues of these drugs (eg, propantheline and orciprenaline [metaproterenol], respectively) are not effective on a long-term basis.

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