What are the possible complications of sinus node dysfunction (SND)?

Updated: Nov 30, 2018
  • Author: Bharat K Kantharia, MD, FRCP, FAHA, FACC, FESC, FHRS; Chief Editor: Mikhael F El-Chami, MD  more...
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The relationship between SND and mortality is difficult to clearly understand, as many individuals with SND have preexisting comorbidities (eg, hypertension, diabetes mellitus, atrial fibrillation) that are known to increase all-cause mortality. [28]

The complications of SND include the following:

  • Sudden cardiac death

  • Syncope

  • Thromboembolic events, including stroke

  • CHF

  • Atrial tachyarrhythmias

About 50% of patients with SND develop tachy-brady syndrome over a lifetime; such patients have a higher risk of stroke and death. However, the incidence of sudden death owing directly to SND is extremely low. [21]

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