What should be avoided by patients with long QT syndrome (LQTS)?

Updated: Nov 29, 2017
  • Author: Ali A Sovari, MD, FACP, FACC; Chief Editor: Mikhael F El-Chami, MD  more...
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Patients with LQTS should avoid participation in competitive sports, strenuous exercise, and stress-related emotions.

These individuals should also avoid the following agents:

  • Anesthetics or asthma medication (eg, epinephrine)
  • Antihistamines (eg, diphenhydramine; terfenadine and astemizole [both recalled from the US market])
  • Antibiotics (eg, erythromycin, trimethoprim and sulfamethoxazole, pentamidine)
  • Cardiac medications (eg, quinidine, procainamide, disopyramide, sotalol, probucol, bepridil, dofetilide, ibutilide)
  • Gastrointestinal medications (eg, cisapride)
  • Antifungal medications (eg, ketoconazole, fluconazole, itraconazole)
  • Psychotropic medications (eg, tricyclic antidepressants, phenothiazine derivatives, butyrophenones, benzisoxazole, diphenylbutylpiperidine)
  • Potassium-losing medications (eg, indapamide, other diuretics; medications for vomiting/diarrhea)

See Treatment and Medication for more detail.

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