Which antiplatelet agent is preferred in non-ST-elevation acute coronary syndrome (unstable angina and NSTEMI), and what is the recommended dosage?

Updated: May 07, 2019
  • Author: A Maziar Zafari, MD, PhD, FACC, FAHA; Chief Editor: Eric H Yang, MD  more...
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Nonenteric-coated chewable aspirin 150 to 325 mg should be given to all patients with NSTE-ACS as soon as possible after presentation.

A maintenance dose of aspirin 75-100 mg daily should be continued indefinitely. [1, 3]

Some clinical data suggest that maintenance dose of aspirin higher than 160 mg daily is associated with increased risk of bleeding with no clear improvement in outcomes. [97, 98]

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