In addition to clopidogrel, which other antiplatelet agents may be used in ST-elevation myocardial infarction (STEMI) (MI, heart attack) management?

Updated: May 07, 2019
  • Author: A Maziar Zafari, MD, PhD, FACC, FAHA; Chief Editor: Eric H Yang, MD  more...
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Other antiplatelet agents that may be used in STEMI management are the intravenous (IV) glycoprotein (GP) IIb/IIIa receptor antagonists. The adjunctive use of GP IIb/IIIa agents at the time of PCI can be considered on an individual basis for a large thrombus burden or inadequate P2Y12 receptor antagonist loading. For patients receiving bivalirudin as the primary anticoagulant, routine adjunctive use of GP IIb/IIIa inhibitors is not recommended but may be considered in selected cases. [2, 4]

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