What is B-type natriuretic peptide (BNP), and what is its role in the workup of myocardial infarction (MI, heart attack)?

Updated: May 07, 2019
  • Author: A Maziar Zafari, MD, PhD, FACC, FAHA; Chief Editor: Eric H Yang, MD  more...
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Answer

B-type natriuretic peptide (BNP) is a 32-amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of cardiomyocytes.

Measurement of BNP or N-terminal pro-B-type natriuretic peptide (NT-pro-BNP) for the diagnosis of acute myocardial infarction (MI) is not recommended for diagnosis of MI, but these biomarkers have utility in risk stratification and prognostication of patients with acute MI who may have congestive heart failure. [38, 60]


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