How has cardiac troponin detection and quantification changed over the years, and when should serial measurements of cardiac troponins be obtained?

Updated: May 07, 2019
  • Author: A Maziar Zafari, MD, PhD, FACC, FAHA; Chief Editor: Eric H Yang, MD  more...
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Answer

Cardiac troponin detection and quantification has improved dramatically over the years as advanced technology allows obtaining cardiac troponin assays running on automated platforms with a high degree of sensitivity. Although implementation of point-of-care testing (POCT) for cardiac biomarkers may seem to improve early diagnosis, [50, 51]  with an advantage of having a shorter turnaround time, this comes at the expense of substantial lower sensitivity and accuracy compared to results obtained from central laboratory testing. [52, 53, 54]


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