How do the signs and symptoms of coronary artery atherosclerosis vary?

Updated: Apr 09, 2021
  • Author: Sandy N Shah, DO, MBA, FACC, FACP, FACOI; Chief Editor: Yasmine S Ali, MD, MSCI, FACC, FACP  more...
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Typical angina symptoms, such as a substernal pressure–like chest pain with radiation to the jaw or left arm may not be present. Less typical symptoms, such as sharp chest pain, dyspnea, diaphoresis, back pain, neck pain, nausea, fatigue, and palpitations may be manifestations of myocardial ischemia. One-third of patients with chest pain with known coronary disease, negative ECG, and biomarkers subsequently have adverse cardiac events. [23] Less typical symptoms are more prevalent in women. In addition, symptoms suggestive of angina may in fact be due to other causes, listed in Differentials.

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