According to the DHHS ART Guidelines, what are the goals of antiretroviral therapy for HIV infection?

Updated: Apr 18, 2019
  • Author: R Chris Rathbun, PharmD, BCPS (AQ-ID), AAHIVP; Chief Editor: John Bartlett, MD  more...
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Answer

Answer

The DHHS ART Guidelines present the following 4 overarching goals:

  • Reduce HIV infection–related morbidity and prolong duration and quality of life

  • Restore and preserve immunologic function

  • Maximally and durably suppress viral load (plasma HIV RNA)

  • Prevent HIV transmission

Suppression of viremia also has the potential to reduce cardiovascular, renal, and hepatic events thought to be related to ongoing inflammation and immune activation from uncontrolled viremia. The risk for both AIDS-related and non–AIDS-associated malignancy may also be reduced by improved immunity. [8]


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