Which nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs) are commercially available in the US for antiretroviral therapy of HIV infection?

Updated: Apr 18, 2019
  • Author: R Chris Rathbun, PharmD, BCPS (AQ-ID), AAHIVP; Chief Editor: John Bartlett, MD  more...
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Answer

Answer

A total of 9 drugs make up the NRTI class; 8 are currently commercially available in the United States, as follows:

  • Abacavir (ABC, Ziagen)

  • Didanosine (ddI, Videx)

  • Emtricitabine (FTC, Emtriva)

  • Lamivudine (3TC, Epivir)

  • Stavudine (d4T, Zerit)

  • Tenofovir DF (TDF, Viread, part of the combination product Stribild and Complera)

  • Tenofovir AF (TAF, part of the combination product Genvoya, Odefsey, and Biktarvy)

  • Zalcitabine (ddC, Hivid; no longer available in the United States)

  • Zidovudine (ZDV, Retrovir; formerly azidothymidine [AZT])


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