Which combination antiretroviral therapies (ARTs) are approved as complete daily regimens to treat HIV infection?

Updated: Apr 18, 2019
  • Author: R Chris Rathbun, PharmD, BCPS (AQ-ID), AAHIVP; Chief Editor: John Bartlett, MD  more...
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Answer

Answer

ART Combination products approved as complete daily regimens, with brand name and generic names/dosages are as follows:

  • Stribild: Elvitegravir (150 mg) + cobicistat (150 mg) + emtricitabine (200 mg) + tenofovir DF (300 mg) qd
  • Genvoya: Elvitegravir (150 mg) + cobicistat (150 mg) + emtricitabine (200 mg) + tenofovir AF (10 mg) qd
  • Symtuza: Darunavir (800 mg) + cobicistat (150 mg) + emtricitabine (200 mg) + tenofovir AF (10 mg) qd
  • Odefsey: Rilpivirine (25 mg) + emtricitabine (200 mg) + tenofovir AF (25 mg) qd
  • Complera: Rilpivirine (25 mg) + emtricitabine (200 mg) + tenofovir DF (300 mg) qd
  • Biktarvy: Bictegravir (50 mg) + emtricitabine (200 mg) + tenofovir AF (25 mg) qd
  • Triumeq: Dolutegravir (50 mg) + abacavir (300 mg) + lamivudine (300 mg) qd
  • Juluca: Dolutegravir (50 mg) + rilpivirine (25 mg) qd (Note: this is a complete once-daily regimen in adults who are virologically suppressed [HIV-1 RNA < 50 copies/mL] on a stable ART regimen for ≥6 months with no history of treatment failure and no known substitutions associated with resistance.)
  • Atripla: Efavirenz (600 mg) + emtricitabine (200 mg) + tenofovir DF (300 mg) (Note: may be use alone as a complete regimen or in combination with other ARTs.)
  • Symfi: Efavirenz (600 mg) + lamivudine (300 mg) + tenofovir DF (300 mg) qd
  • Symfi Lo: Efavirenz (400 mg) + lamivudine (300 mg) + tenofovir DF (300 mg) qd
  • Delstrigo: Doravirine (100 mg) + lamivudine (300 mg) + tenofovir DF (300 mg) qd

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