What are the fosamprenavir (Lexiva) dosing guidelines for antiretroviral therapy of HIV infection?

Updated: Apr 18, 2019
  • Author: R Chris Rathbun, PharmD, BCPS (AQ-ID), AAHIVP; Chief Editor: John Bartlett, MD  more...
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Answer

Answer

Fosamprenavir (Lexiva):

  • Dosage forms: 700-mg tablet; 50-mg/mL oral suspension
  • Adult dose: 700 mg bid + ritonavir 100 mg PO bid or 1400 mg PO bid or 1400 mg + ritonavir 100-200 mg PO qd (approved only for antiretroviral treatment–naïve patients); 700 mg bid + ritonavir 100 mg PO bid (treatment-experienced patients)
  • Comments: Suspension, take without food; boosted with RTV, take with food
  • Adverse events: Rash, nausea, vomiting, diarrhea, hyperlipidemia, hyperglycemia

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