What are the doravirine (Pifeltro) dosing guidelines for antiretroviral therapy of HIV infection?

Updated: Apr 18, 2019
  • Author: R Chris Rathbun, PharmD, BCPS (AQ-ID), AAHIVP; Chief Editor: John Bartlett, MD  more...
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Answer

Answer

Doravirine (Pifeltro):

  • Dosage forms: 100-mg tablet
  • Adult dose: 100 mg PO qd
  • Comments: Take with or without food; coadministration with strong CYP3A inducers may decrease systemic exposure and lead to loss of therapeutic effect and possible HIV resistance
  • Adverse events: Immune reconstitution syndrome

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