What is the stavudine (Zerit) dosing guidelines for antiretroviral therapy of HIV infection?

Updated: Apr 18, 2019
  • Author: R Chris Rathbun, PharmD, BCPS (AQ-ID), AAHIVP; Chief Editor: John Bartlett, MD  more...
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Answer

Answer

Stavudine (Zerit) (dosage adjustment with renal impairment required):

  • Dosage forms: 15-mg, 20-mg, 30-mg, 40-mg capsule; 1-mg/mL oral solution
  • Adult dose: >60 kg, 40 mg PO bid; < 60 kg, 30 mg PO bid
  • Comments: Take without regard to meals
  • Adverse events: Peripheral neuropathy, pancreatitis, lactic acidosis, lipoatrophy, hyperlipidemia

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