What are the lamivudine (Epivir) dosing guidelines for antiretroviral therapy of HIV infection?

Updated: Apr 18, 2019
  • Author: R Chris Rathbun, PharmD, BCPS (AQ-ID), AAHIVP; Chief Editor: John Bartlett, MD  more...
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Answer

Answer

Lamivudine (Epivir) (dosage adjustment with renal impairment required):

  • Dosage forms: 150-mg, 300-mg tablet; 10-mg/mL oral solution
  • Adult dose: 300 mg PO qd or 150 mg PO bid
  • Comments: Take without regard to meals
  • Adverse events: Minimal toxicity, severe acute exacerbation of hepatitis may occur with HBV-coinfection upon discontinuation

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