What are the didanosine (Videx, Videx EC) dosing guidelines for antiretroviral therapy of HIV infection?

Updated: Apr 18, 2019
  • Author: R Chris Rathbun, PharmD, BCPS (AQ-ID), AAHIVP; Chief Editor: John Bartlett, MD  more...
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Answer

Answer

Didanosine (Videx, Videx EC) (dosage adjustment with renal impairment required):

  • Dosage forms: 125-mg, 200-mg, 250-mg, 400-mg delayed-released capsule; 10-mg/mL powder for solution
  • Adult dose: >60 kg, 400 mg PO qd; < 60 kg, 250 mg PO qd
  • Comments: Take 30 min ac or 2 hr pc; for oral solution, divide daily dose bid
  • Adverse events: Peripheral neuropathy, pancreatitis, nausea, lactic acidosis

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