What are the abacavir (Ziagen) dosing guidelines for antiretroviral therapy of HIV infection?

Updated: Apr 18, 2019
  • Author: R Chris Rathbun, PharmD, BCPS (AQ-ID), AAHIVP; Chief Editor: John Bartlett, MD  more...
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Answer

Answer

Abacavir (Ziagen):

  • Dosage form: 300-mg tablet; 20-mg/mL oral solution
  • Adult dose: 600 mg PO qd or 300 mg PO bid
  • Comments: Take without regard to meal
  • Adverse events: Hypersensitivity reaction (may include fever, rash, nausea, vomiting, diarrhea, malaise, shortness of breath, cough, pharyngitis); patients positive for HLA-B*5701 are at highest risk for hypersensitivity (perform HLA screening before initiating)

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