Which medications in the drug class Antipsychotic Agent are used in the treatment of Narcissistic Personality Disorder?

Updated: May 16, 2018
  • Author: Sheenie Ambardar, MD; Chief Editor: David Bienenfeld, MD  more...
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Answer

Antipsychotic Agent

Atypical antipsychotic agents such as risperidone may be used in adult patients with NPD to treat transient psychosis, mood lability, and poor impulse control. The response to antipsychotics is less dramatic than that seen in in true psychotic axis I disorders, but symptoms such as anxiety, hostility, and sensitivity to rejection may be reduced. Antipsychotics are typically used for a short time while the symptoms are active.

Risperidone (Risperdal, Risperdal Consta IM Injection, Risperdal M-Tab)

Risperidone binds to dopamine D2 receptors with a 20 times lower affinity than that for serotonin 5-HT2 receptors. It mitigates negative symptoms of psychoses and reduces the incidence of extrapyramidal adverse effects.


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