What is the clinical presentation of Wellens syndrome?

Updated: Jan 25, 2018
  • Author: Benjamin B Mattingly, MD; Chief Editor: Erik D Schraga, MD  more...
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Wellens syndrome represents stenosis of the proximal left anterior descending coronary artery (LAD), and patients typically present with symptoms or complaints consistent with coronary artery disease (CAD). Generally, the history is most consistent with unstable angina. Angina can have varying presentations, but the classic presentation includes the following complaints:

  • Chest pain described as pressure, tightness, or heaviness

  • Pain that is typically induced by activity and relieved by rest

  • Radiation of pain to the jaw, shoulder, or neck

  • May experience multiple associated symptoms, including (but not limited to) diaphoresis, nausea, vomiting, and fatigue

Elderly, diabetic, and female patients are more likely to present with atypical symptoms.

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