Which medications in the drug class Beta-Blockers, Beta-1 Selective are used in the treatment of Atrial Flutter?

Updated: Nov 18, 2019
  • Author: Lawrence Rosenthal, MD, PhD, FACC, FHRS; Chief Editor: Jeffrey N Rottman, MD  more...
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Answer

Beta-Blockers, Beta-1 Selective

These agents are used to slow ventricular response by slowing AV nodal conduction during atrial fibrillation or flutter. They are also indicated for use in conjunction with class IA and IC antiarrhythmics, which slow atrial fibrillation or flutter rate and may cause more rapid ventricular response.

Beta blockers currently play more of a secondary role in rate control in atrial flutter and fibrillation. Patients receiving these agents require careful monitoring of blood pressure.

Metoprolol (Lopressor, Toprol XL)

Metoprolol is a selective beta1-adrenergic receptor blocker that decreases automaticity of contractions. During IV administration, carefully monitor blood pressure, heart rate, and ECG.

Atenolol (Tenormin)

Atenolol selectively blocks beta1 receptors, with little or no effect on beta2 receptors.

Esmolol (Brevibloc)

Esmolol (Brevibloc)

Esmolol is excellent for use in patients at risk for experiencing complications from beta-blockade, particularly those with reactive airway disease, mild-to-moderate LV dysfunction, and/or peripheral vascular disease. Its short half-life of 8 min allows titration to desired effect and quick discontinuation if necessary.


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