What is the role of therapeutic international normalized ratio (INR) in the treatment of atrial flutter (AFL)?

Updated: Nov 18, 2019
  • Author: Lawrence Rosenthal, MD, PhD, FACC, FHRS; Chief Editor: Jeffrey N Rottman, MD  more...
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Patients need to maintain a therapeutic international normalized ratio (INR) for 3 weeks before conversion and for at least 4 weeks after conversion to sinus rhythm. Long-term anticoagulation is recommended for patients with chronic atrial flutter. Closely monitor the patient’s anticoagulation therapy, with a target INR of 2-3. Take special care when additional medications (including antibiotics) are added because they may dramatically alter the INR in patients treated with warfarin.

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