What is the role of an anatomic or functional block in the pathogenesis of atrial flutter (AFL) in animal models?

Updated: Nov 18, 2019
  • Author: Lawrence Rosenthal, MD, PhD, FACC, FHRS; Chief Editor: Jeffrey N Rottman, MD  more...
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Answer

Animal models have been used to demonstrate that an anatomic block (surgically created) or a functional block of conduction between the superior vena cava and the inferior vena cava, similar to the crista terminalis in the human right atrium, is key to initiating and maintaining the arrhythmia.


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