What are the treatment options for secondary burning mouth syndrome (BMS)?

Updated: Apr 15, 2021
  • Author: Vincent D Eusterman, MD, DDS; Chief Editor: Arlen D Meyers, MD, MBA  more...
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Treatments for secondary burning mouth syndrome (BMS) include the following:

  • Discontinuation of medications that may cause xerostomia, such as anticholinergics or psychotropics

  • Substitution of medications that may cause oral burning (If an ACE inhibitor, ARB, or antiretroviral is suspected, trying another medication in the same class is reasonable.)

  • Adjustment of levothyroxine dosing

  • Oral nystatin

  • Abstinence from smoking and oral tobacco use

  • Avoidance of allergens

  • Adjustment of dentures (refitting and/or substituting materials)

  • Chewing sorbitol-containing gum to stimulate saliva [70]

  • Pyridostigmine, Pilocarpine, or other sialogogues

  • B vitamin supplementation

  • Zinc supplementation [35]

  • Iron supplementation

  • Folate supplementation

  • Neuropathic analgesics

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