What is the role of topical clonazepam in the treatment of burning mouth syndrome (BMS)?

Updated: Apr 15, 2021
  • Author: Vincent D Eusterman, MD, DDS; Chief Editor: Arlen D Meyers, MD, MBA  more...
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A literature review by Miziara et al of treatment studies suggested that topical clonazepam, although not a cure, offers short-term improvement of burning mouth syndrome, with studies on alpha-lipoic acid and cognitive therapy showing their effectiveness as well. However, the investigators found few randomized, controlled studies demonstrating the long-term effectiveness of alpha-lipoic acid, although they reported that research did indicate that cognitive therapy produces lasting results. [68]

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