What conditions should be included in the differential diagnoses of burning mouth syndrome (BMS)?

Updated: Jan 22, 2018
  • Author: Vincent D Eusterman, MD, DDS; Chief Editor: Arlen D Meyers, MD, MBA  more...
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Answer

Answer

Distinguishing primary (idiopathic) burning mouth syndrome (BMS) from secondary burning mouth syndrome (BMS) is important. The following conditions may produce BMS-like symptoms:

  • Candidiasis [38]

  • Sjögren Syndrome

  • Scleroderma

  • GERD

  • Anemia

  • Diabetes

  • Vitamin deficiency (B1, B2, B6, B12, folate, iron)

  • Hypothyroidism

  • Multiple sclerosis

  • Anxiety

  • Dehydration

  • Mouth breathing/nasal obstruction

  • Alcohol-based mouthwash

  • Medication reaction (eg, ACE inhibitors, ARBs, antiretrovirals, psychotropic, anticholinergic, clonazepam, [48] chemotherapeutic agents)

  • Radiation-induced stomatitis

  • Aphthous stomatitis

  • Contact stomatitis

  • Erosive lichen planus

  • Pemphigoid

  • Pemphigus

  • Geographic tongue

  • Mandibular fracture

  • Neoplasia

  • Impacted teeth

  • Infections of bone, teeth, or implants

  • Ciguatera neurotoxin exposure [49]

  • Chewing tobacco use

  • Areca nut extract exposure [50]

  • Leukoplakia

  • Bacterial infection [51]


Source Article: Burning Mouth Syndrome: Differential Diagnosis

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