What is the role of menopause in the etiology of burning mouth syndrome (BMS)?

Updated: Apr 15, 2021
  • Author: Vincent D Eusterman, MD, DDS; Chief Editor: Arlen D Meyers, MD, MBA  more...
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Menopause, whether surgical or physiological, is associated with a higher prevalence of burning mouth syndrome (BMS), and, while the mechanism is unclear, hormonal alterations in oral mucosa have been suggested as a cause. Estrogen has documented effects on oral mucosa, and deprivation may lead to atrophic changes thereby altering stimulation of the nerve endings within the epithelium. [30] Alternatively, atrophic epithelia may be more prone to inflammation.

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