How do the 5-year treatment outcomes aortic stenosis (AS) vary between percutaneous transcatheter aortic-valve replacement (TAVR) and surgical aortic valve replacement (SAVR)?

Updated: May 07, 2019
  • Author: Xiushui (Mike) Ren, MD; Chief Editor: Terrence X O'Brien, MD, MS, FACC  more...
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Five-year outcomes from the PARTNER trial showed similar outcomes between high-risk patients with aortic stenosis who underwent TAVR and those who underwent surgical aortic valve replacement (SAVR). [38] At 5 years, risk of death was 67.8% in the TAVR group versus 62.4% in the SAVR group. Neither group reported structural valve deterioration requiring surgical valve replacement. However, moderate or severe aortic regurgitation occurred in 40 of 280 (14%) patients in the TAVR group but in only 2 of 228 (1%) patients in the SAVR group; this was associated with increased 5-year risk of mortality in the TAVR group. [38]

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