How is differentiation syndrome prevented in acute promyelocytic leukemia (APL)?

Updated: May 03, 2019
  • Author: Sandy D Kotiah, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

For high risk patients (WBC >10,000/μL), prophylaxis against differentiation syndrome is with corticosteroids (prednisone or dexamethasone) with the dose tapered over several days.


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