What is the recurrence risk of preeclampsia?

Updated: Nov 29, 2018
  • Author: Kee-Hak Lim, MD; Chief Editor: Ronald M Ramus, MD  more...
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Answer

Answer

In general, the recurrence risk of preeclampsia in a woman whose previous pregnancy was complicated by preeclampsia near term is approximately 10%. [48] If a woman has previously suffered from preeclampsia with severe features (including HELLP [hemolysis, elevated liver enzyme, low platelets] syndrome and/or eclampsia), she has a 20% risk of developing preeclampsia some time in her subsequent pregnancy. [96, 97, 98, 99, 100, 101]

If a woman has had HELLP syndrome or eclampsia, the recurrence risk of HELLP syndrome is 5% [97] and of eclampsia it is 2%. [99, 100, 101] The earlier the disease manifests during the index pregnancy, the higher the chance of recurrence rises. If preeclampsia presented clinically before 30 weeks' gestation, the chance of recurrence may be as high as 40%. [102]

The fullPIERS model has been validated and was successful in predicting adverse outcomes in advance; therefore, it is potentially able to influence treatment choices before complications arise. [103]


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