What is the role of nifedipine in the treatment of preeclampsia?

Updated: Nov 29, 2018
  • Author: Kee-Hak Lim, MD; Chief Editor: Ronald M Ramus, MD  more...
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Answer

Answer

Calcium channel blockers act on arteriolar smooth muscle and induce vasodilatation by blocking calcium entry into the cells. Nifedipine is the oral calcium channel blocker that is used in the management of hypertension in pregnancy. The dosage of nifedipine is 10 mg PO every 15-30 minutes, with a maximum of 3 doses. The side effects of calcium channel blockers include tachycardia, palpitations, and headaches. Concomitant use of calcium channel blockers and magnesium sulfate is to be avoided. Nifedipine is commonly used postpartum in patients with preeclampsia, for BP control. [13, 70]


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