What are the adverse effects of hydralazine in the treatment of preeclampsia?

Updated: Nov 29, 2018
  • Author: Kee-Hak Lim, MD; Chief Editor: Ronald M Ramus, MD  more...
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Answer

Answer

The side effects of hydralazine are headache, nausea, and vomiting. Importantly, hydralazine may result in maternal hypotension, which can subsequently result in a nonreassuring fetal heart rate tracing in the fetus. [13]

In a meta-analysis, Magee et al pointed out that hydralazine was associated with worse maternal and perinatal outcomes than were labetalol and nifedipine. Furthermore, hydralazine was associated with more maternal side effects than were labetalol and nifedipine. [70]


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