What is the role of lab testing in the diagnosis of preeclampsia?

Updated: Nov 29, 2018
  • Author: Kee-Hak Lim, MD; Chief Editor: Ronald M Ramus, MD  more...
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Answer

Answer

All women who present with new-onset hypertension should have the following laboratory tests:

  • Complete blood cell (CBC) count

  • Serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels

  • Serum creatinine

  • Uric acid

In addition, a peripheral smear should be performed, serum lactate dehydrogenase (LDH) levels should be measured, and an indirect bilirubin should be carried out if HELLP (hemolysis, elevated liver enzyme, low platelets) syndrome is suspected. Although a coagulation profile (prothrombin time [PT], activated partial [aPTT], and fibrinogen) should also be evaluated, the clinical use of routine evaluation is unclear when the platelet count is 100,000/mm3 or more with no evidence of bleeding. [4]


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