What causes placental hypoperfusion or ischemia in preeclampsia?

Updated: Nov 29, 2018
  • Author: Kee-Hak Lim, MD; Chief Editor: Ronald M Ramus, MD  more...
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Placental hypoperfusion or ischemia in preeclampsia has many causes. Preexisting vascular disorders, such as hypertension and connective tissue disorders, can result in poor placental circulation. In cases of multiple gestation or increased placental mass, it is not surprising for the placenta to become underperfused. However, most women who develop preeclampsia are healthy and do not have underlying medical conditions. In this group of women, abnormally shallow placentation has been shown to be responsible for placental hypoperfusion. (See Placentation in Preeclampsia.)

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