Which risk factors have a major role in the etiology of preeclampsia?

Updated: Nov 29, 2018
  • Author: Kee-Hak Lim, MD; Chief Editor: Ronald M Ramus, MD  more...
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The mechanisms by which preeclampsia occurs is not certain, and numerous maternal, paternal, and fetal factors have been implicated in its development. The factors currently considered to be the most important include the following [20] :

  • Maternal immunologic intolerance

  • Abnormal placental implantation

  • Genetic, nutritional, and environmental factors

  • Cardiovascular and inflammatory changes

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