What is the role of lab testing in the diagnosis of pulmonary veno-occlusive disease (PVOD)?

Updated: Oct 16, 2018
  • Author: Hakim Azfar Ali, MD; Chief Editor: Zab Mosenifar, MD, FACP, FCCP  more...
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Answer

Laboratory parameters are generally unremarkable and not helpful in the diagnostic workup, although microangiopathic hemolytic anemia, proteinuria, and elevations in serum immunoglobulin G and M concentrations have been reported. Note, however, that laboratory results are more abnormal in cases of PVOD associated with autoimmune disease. The level of brain natriuretic peptide is expected to be high in patients with overt right-sided heart failure.


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